2022 The Game · Michigan 45, Ohio State 23

Michigan beat Ohio State 45-23 in Columbus, the first Wolverine win in The Horseshoe since 2000 and the second of what would become four consecutive series wins. Donovan Edwards' 75-yard touchdown run sealed it; the Wolverines' offensive line made the line of scrimmage their own all afternoon. Day's first loss as head coach in his home stadium, and the start of the criticism that would compound through every subsequent rivalry result. The Harbaugh program's identity — downhill rushing, defensive nastiness, post-play extracurricular willingness — was set publicly here.